Selank

Overview

Torsena is a European supplier of research-grade Selank dedicated to qualified laboratories and research institutions. Orders ship from EU-based stock with batch documentation available upon request.

Lot & Supply Format

• Purity ≥99% verified by HPLC/MS analysis
• Mannitol-free formulation (no bulking agents or buffers)
• Lyophilized peptide in sealed glass research vials
• Single vials and bulk quantities available
• CoA transparency: batch-specific certificate of analysis available upon request
• Shipped from Europe with temperature-appropriate packaging

What is Selank?

Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin. The tuftsin core (Thr-Lys-Pro-Arg) is extended with a C-terminal Pro-Gly-Pro motif. Like Semax, Selank was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Both peptides share the Pro-Gly-Pro stabilization strategy but are built on entirely different parent sequences.

Tuftsin is a naturally occurring tetrapeptide derived from the Fc domain of immunoglobulin G (IgG). It was originally characterized for its role in phagocyte activation and immune signaling. Selank extends this immunopeptide scaffold with the Pro-Gly-Pro motif to enhance metabolic stability. The result is a research tool that bridges immunological and neurological signaling investigation.

Selank is studied in research models examining the interface between immune signaling and central nervous system function. This area of investigation is often referred to as neuroimmune or psychoneuroimmunological research.

Supplied exclusively for in-vitro and ex-vivo research by qualified laboratories. Not intended for human or animal administration.

Mechanistic Overview

Neuroimmune Signaling
Selank has been investigated in experimental models examining the relationship between immune peptide signaling and CNS function. Published research describes effects on interleukin-6 (IL-6) expression and other cytokine signaling pathways. These effects have been characterized in both peripheral immune and central nervous system tissue models.

Enkephalin Metabolism
Research has characterized Selank’s interactions with enkephalin-degrading enzyme systems. The primary targets described in published studies are carboxypeptidase and aminopeptidase pathways. Findings describe modulation of endogenous enkephalin turnover rates in experimental models. This positions the compound as a tool for investigating opioid peptide metabolism and its relationship to anxiolytic-like behavioral phenotypes in preclinical models.

GABAergic Pathway Research
In vitro and preclinical studies have examined Selank in models of GABAergic neurotransmission. Published research describes interactions with GABA receptor subunit expression and benzodiazepine binding site allosteric modulation. These studies position Selank as a reference compound in research examining peptidergic modulation of inhibitory neurotransmitter systems.

Selank vs Semax

Characteristic	Selank	Semax
Parent Peptide	Tuftsin (immunopeptide)	ACTH(4-10) (neuropeptide)
Stabilizing Motif	Pro-Gly-Pro (C-terminal)	Pro-Gly-Pro (C-terminal)
Primary Research Target	GABAergic / enkephalin / cytokine	BDNF / dopaminergic / cholinergic
Behavioral Phenotype Studied	Anxiolytic-like	Cognitive / nootropic-like
CAS Number	129954-34-3	80714-61-0

For paired neuropeptide research, see also our Semax research peptide.

Reconstitution & Storage

Lyophilized Selank is stable at -20°C for long-term storage. Reconstitution for in-vitro work is typically performed using bacteriostatic water or sterile saline. Reconstituted aliquots are generally stored at 2-8°C for short-term use. For extended storage, aliquot and freeze at -20°C to preserve peptide integrity. Researchers should follow institutional SOPs for handling lyophilized peptides.

Why Torsena

• Analytical Testing — Purity verified by third-party HPLC and mass spectrometry
• No Fillers — Mannitol-free, no bulking agents or buffer salts
• Batch Transparency — Certificate of Analysis available upon request
• Consistent Availability — Single vials and bulk quantities maintained in stock
• EU Distribution — Shipped from European fulfillment with tracked courier
• Full Documentation — Batch-specific CoA and MSDS available for institutional procurement

Product Specifications

Chemical Name: Selank
Synonyms: TP-7, Selanc
CAS Number: 129954-34-3
Molecular Formula: C₃₃H₅₇N₁₁O₉
Molecular Weight: 751.87 g/mol
Purity: ≥99% (HPLC/MS)
Physical Form: White lyophilized powder
Additives: None (mannitol-free)
Intended Use: In-vitro / ex-vivo laboratory research only

Amino Acid Sequence

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Parent Sequence: Tuftsin = Thr-Lys-Pro-Arg
Stabilizing Extension: Pro-Gly-Pro (C-terminal)
Peptide Length: 7 amino acids
Type: Linear

Analytical Transparency

All Torsena research materials are tested for purity and identity by HPLC and mass spectrometry analysis. Batch-specific Certificates of Analysis are available upon request for institutional procurement.

• Reverse-phase HPLC purity determination
• Mass spectrometry identity confirmation
• Appearance and solubility verification
• Endotoxin screening (where applicable)

Related Research Compounds

Researchers studying neuropeptide signaling and CNS function may also be interested in:

• Semax — ACTH(4-10) analog for cognitive and BDNF-related research